Dr. Md. Morshedul Alam

Name: Dr. Md. Morshedul Alam

Title: Dr.

Designation: Assistant Professor (Genetic Engineering & Biotechnology)

Contact: +88-09666776868 (Ext. 459)

Email: morshed.gebt@bsmrmu.edu.bd

Blood Group: AB+

Present address: Dept. of Genetic Engineering & Biotechnology Bangabandhu Sheikh Mujibur Rahman Maritime University Mirpur 12 Dhaka 1216.

Permanent Address: Village+Post: Khamarpara, PS: Sreepur, Magura 7610.

About: https://www.researchgate.net/profile/Md_Morshedul_Alam ORCID ID: https://orcid.org/0000-0003-1564-969X
Research Area:

1. Cancer epigenetics and Oxidative stress response in Aging-associated diseases (Cancer, Diabetes, Neurological disorders).

2. Marine bioactive compounds isolation, identification and clarification of their medicinal and nutritional value in murine model.

Teaching:

Marine Biotechnology, Marine Microbiology, Genetics & Immunology, Aquatic Biotechnology, Medical Biotechnology, Molecular Biology, Animal Biotechnology & Stem Cell Engineering, Pharmaceutical Biotechnology, Environmental Biotechnology, Microbial Genetics, Virology & Oncology, Plant Tissue Culture, Bioenergetics & Metabolism, Cell Biology, Molecular Genetics, Plant Physiology. Cell Signaling, Developmental Biology.   

Academic Qualifications:
Sl Exam Institute Year Result
1 PhD in Medicine Tohoku University, Japan 2017 Awarded
2 MSc in Biotechnology & Genetic Engineering Islamic University, Kushtia 2005 1st Class 4th in merit
3 BSc in Biotechnology & Genetic Engineering Islamic University, Kushtia 2004 1st Class 3rd in merit
4 HSC in Science Sripur Degree College, Magura 1999 1st Division
5 SSC in Science Sreepur MC Pilot Secondary School, Magura 1997 1st Division (*Star)
In Service Courses, Symposium, Workshop and Seminar:
Sl Title Institute Year Remarks
1 The Foundation of Quality Assurance: Designing effective quality assurance systems in HE institutions in Bangladesh Conducted under Continuous Professional Development (CPD) certification service by BSMRMU IQA, Dhaka, Bangladesh 2019 Workshop
2 Engaging University Faculties for Capacity Building in Achieving SDGs on Sustainable Food and Agriculture organized by Food and Agriculture Organization (FAO), Swedish Academy of Agriculture (SLU) and BARD, Comilla, Bangladesh 2019 Workshop
3 Compliance education for preventing fraud or misuse of research funds Tohoku University, Japan 2019 Workshop
4 Compliance education for preventing fraud or misuse of research funds Tohoku University, Japan 2018 Workshop
5 Responsible Research Act Tohoku University, Japan 2015 Workshop
6 Research aimed at 02_people: foundation ed Tohoku University, Japan 2015 Workshop
7 Regulations on Animal Experiments and Related Activities in Tohoku University Tohoku University, Japan 2014 Workshop
8 Genetic Recombination Experiment Regulations Tohoku University, Japan 2013 Workshop
9 Compliance education for preventing fraud or misuse of research funds Tohoku University, Japan 2020 Workshop
Professional Memberships:

 

Membership

  • Japan Student Services Organization (JASSO), Japan (from October-2017).
  • Cancer Epigenetics Society (CES), Viena, Austria (from July-2017).
  • Japan Biochemical Society (JBS) member, (from May-2016).
  • Biotechnology & Genetic Engineering department student’s Alumni Association, Islamic Univeristy, Kushtia (from 2015).
  • Institute of Development, Aging and Cancer (IDAC) Alumni Association, IDAC, Tohoku University, Sendai, Japan (from 2014).
  • Country Representative of Bangladesh, Jeju International Student Organization (JISO), JNU, Korea (2012).
  • “Bangladesh Association for Plant Tissue Culture & Biotechnology (BAPTC&B)”, Dhaka University, Dhaka, Bangladesh.
  • “Asian Network of Research on Anti-diabetic Plants (ANRAP)”, BIRDEM, Dhaka-1000, Bangladesh.
  • “Young Biotechnologists of Bangladesh (YoungBB)”, Dhaka, Bangladesh.
  • “Bangladesh Association for Biotechnology (BABT)”, BAU, Mymanshingh, Bangladesh. (Former member)
  • “Biotech Association” of Islamic University, Kushtia, Bangladesh. (Former member)
Awards:

Research Grants:

2021/07: UGC research fellowship grant, Bangladesh (Associate Project Director).

2019/10: UGC research fellowship grant, Bangladesh (Associate Project Director).

2018/07: Grant-in-Aid for JSPS Research Fellow FY2017, Japan Society for the Promotion of

               Science (JSPS), Japan. (https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17F17116/)

2017/07: Grant-in-Aid for JSPS Research Fellow FY2017, Japan Society for the Promotion of

               Science (JSPS), Japan. (https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17F17116/)

2015/10: 2015 Year’s (Heisei-27) Booster Research Grant, Tohoku University, Sendai, Japan.

2013/10: 2013 year’s (Heisei-25) Starter Research Grant, Tohoku University, Sendai, Japan.

2013/07: IDAC Research Grant Award, IDAC, Tohoku University, Sendai, Japan.

 

Academic Awards and Fellowships


  1. Outstanding Scientist Award-2021, Coimbatore, India.
  2. Tokyo Biochemical Research Foundation (TBRF) Postdoctoral Fellowship-2019 in IDAC, Tohoku University, Japan (2019.01)
  3. Appreciation Award by JSPS Science Dialogue Program-2017 (2017.12).
  4. FY2017 Japan Society for the Promotion of Science (JSPS) Postdoctoral Fellowship in Japan (Standard), IDAC, Tohoku University, Japan (2017.01).
  5. Monbukagakusho (MEXT) scholarship, Tohoku University, Japan (10/2012 - 03/2017).
  6. BK21 scholarship, Jeju National University, Jeju, Korea (2011).
  7. KHS (KNU Honors Scholarship), Kyungpook National University, Daegu, Korea (2009).
  8. Awarded “Incentive Stipend” by The Bangladesh Sena Kallyan Sangstha, Sena Kallyan Bhaban, Motizhil Commercial area, for obtaining brilliant result at the graduation level from Islamic University, Kushtia-7003, Bangladesh (2007).
  9. University grants Commission (UGC) Scholarship from the Islamic University, Kushtia-7003, Bangladesh (2007 & 2009).
  10. Awarded ‘A’ Grade scholarship from the Islamic University, Kushtia-7003, Bangladesh, due to Bright Academic Performance in the B.Sc. (Hons.) level (2002, 2003, 2004 & 2005).
Experience:
Sl Designation Organization From To Remarks
1 Assistant Professor BSMR Maritime University, Dhaka, Bangladesh 18-Aug-2019 On going
2 TBRF Postdoctoral fellow Tohoku University, Japan 03-May-2019 15-Aug-2019
3 JSPS Postdoctoral fellow (Standard) Tohoku University, Japan 03-May-2017 02-May-2019
4 Research Assistant Tohoku University, Japan 01-Apr-2014 31-Mar-2016
5 Research Fellow Tohoku University, Japan 01-Oct-2012 31-Mar-2013
6 Research Fellow Jeju National University, Korea 01-Sep-2011 31-Aug-2012
7 Research Fellow Kyungpook National University, Korea 01-Mar-2009 28-Feb-2010
Publications:
  1. Md. Morshedul Alam*. “Prospect of marine bioactive peptides as DPP4 inhibitor.” Oceanography and Fisheries Open Access Journal. 2022; April, 14(4). (IF: 0.804)
  2. Md. Morshedul Alam*, Kanchan Chakma, Shahriar Mahmud, Mohammad Nazir Hossain, M. Rezaul Karim, Md. Ariful Amin. “Multiomics analysis of altered NRF3 expression reveals poor prognosis in cancer.” Informatics in Medicine Unlocked. 2022; February, 29:100892. (IF: 3.373)

3.     Keito Okazaki, Hayato Anzawa, Zun Liu, Ota Nao, Hiroshi Kitamura, Yoshiaki Onodera, Md. Morshedul Alam, Daisuke Matsumaru, Takuma Suzuki, Fumiki Katsuoka, Shu Tadaka, Ikuko Motoike, Mika Watanabe, Kazuki Hayasaka, Akira Sakurada, Yoshinori Okada, Masayuki Yamamoto, Takashi Suzuki, Kengo Kinoshita, Hiroki Sekine, Hozumi Motohashi. “Enhancer remodeling promotes tumor-initiating activity in NRF2-activated Non-small Cell Lung Cancers”. Nature Communications. 2020; November, (11):5911. (IF: 14.919)

4.     Md. Morshedul Alam*, Kanchan Chakma, Shahriar Mahmud, Mohammad Nazir Hossain, Tamim Ahsan. “A systemic analysis reveals TRIM24-SMARCC1 dependent poor prognosis of Hepatocellular Carcinoma”. Informatics in Medicine Unlocked. 2020; October, 21(100467):1-12. (IF:3.373)

5.     Hiroki Sekine, Keito Okazaki, Koichiro Kato, Md. Morshedul Alam, Hiroki Shima, Fumiki Katsuoka, Tadayuki Tsujita, Norio Suzuki, Akira Kobayashi, Kazuhiko Igarashi, Masayuki Yamamoto, Hozumi Motohashi; “O-GlcNAcylation signal confers resistance to proteasome inhibitors on cancer cells by increasing NRF1 stability”. Molecular and Cellular Biology. 2018; June. (IF: 4.272)

6.     Hozumi Motohashi, Tomoaki Ida, Md. Morshedul Alam, Hiroshi Kitamura, Takaaki Akaike. Bright and dark sides of KEAP1-NRF2 system in carcinogenesis. Free Radical Biology and Medicine. 2018; May, 120 (Supl-1): S18. (IF: 7.376)

7.     Takaaki Akaike, Tomoaki Ida, Fan-Yan Wei, Motohiro Nishida, Yoshito Kumagai, Md. Morshedul Alam, Hideshi Ihara, Tomohiro Sawa, Tetsuro Matsunaga, Shingo Kasamatsu, Akiyuki Nishimura, Masanobu Morita, Kazuhito Tomizaawa, Akira Nishimura, Satoshi Watanabe, Kenji Inaba, Hiroshi Shima, Nobuhiro Tanuma, Minkyung Jung, Shigemoto Fuji, Yasuo Watanabe, Masaki Ohmuraya, Peter Nagy, Martin Feelisch, Jon M. Fukuto, Hozumi Motohashi. “Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics”. Nature Communications. 2017; October, (8):1177. (IF: 14.919)

8.     Md. Morshedul Alam, Keito Okazaki, Linh Thi Thao Nguyen, Nao Ota, Hiroshi Kitamura, Shohei Murakami, Hiroki Shima, Kazuhiko Igarashi, Hiroki Sekine and Hozumi Motohashi; “Glucocorticoid receptor signaling represses the antioxidant response by inhibiting histone acetylation mediated by the transcriptional activator NRF2.” Journal of Biological Chemistry. 2017; March, 292(18): 7519-7530.
 (IF: 5.157)

9.     Dong-Sung Lee, Eun-Sol Lee, Md. Morshedul Alam, Jun-Hyeog Jang, Ho-Sub Lee, Hyuncheol Oh, Youn-Chul Kim, Zahid Manzoor, Young-Sang Koh, Dae-Gil Kang and Dae Ho Lee; “Soluble DPP-4 up-regulates toll-like receptors and augments inflammatory reactions, which are ameliorated by vildagliptin or mannose-6-phosphate.” Metabolism: Clinical & Experimental. 2016; February, 65(2): 89-101. (IF: 8.694)

10.  Maki Goto, Hiroshi Kitamura, Md. Morshedul Alam, Nao Ota, Takeshi Haseba, Toshio Akimoto, Akio Shimizu, Teruko Takano-Yamamoto, Masayuki Yamamoto and Hozumi Motohashi; “Alcohol dehydrogenase 3 contributes to the protection of liver from nonalcoholic steatohepatitis.” Genes to Cells. 2015; March, 20(3): 1-17. (IF: 2.048)

11.  Jo-Heon Kim, Md. Morshedul Alam, Doek Bae Park, Moonjae Cho, Seung-Hong Lee, You-Jin Jeon, Dae-Yeul Yu, Tae Du Kim, Ha Young Kim, Chung Gu Cho, Dae Ho Lee; “The effect of metformin treatment on CRBP-1 level and cancer development in the liver of HBx transgenic mice.” Korean Journal of Physiology & Pharmacology. 2013; October, 17(5): 455-461. (IF: 2.016)

12.  Md. Morshedul Alam, Sang Ah Lee, Gwanpyo Koh and Dae Ho Lee; Changes of Hepatic Cellular Retinol-Binding Protein-I (CRBP-I) in Relation to Fatty Liver Diseases. Journal of Diabetes Investigation, 2012; November, 3 (suppl-1):159. (IF- 4.232)

  1. Md. Morshedul Alam*, Redwan Ahmed, Md. Ariful Amin, Mohammad Nazir Hossain. “Development and validation of a novel customized medium for the marine microbial culture.” Bioresearch Communications. 2021; July, 7(2): 999-1003.

14.  Md. Farzanoor Rahman, Md. Abdul Alim, Tamim Ahsan, Toufiqul Islam, Md. Morshedul Alam*, Mohammad Nazir Hossain. “Screening of potential bioactive compounds from Padina gymnospora found in the coast of St. Martin Island of Bangladesh.” Journal of Marine Biology and Aquaculture. 2021, March, 7(1): 1-7. (IF: 0.565)

15.  Tamim Ahsan, Toufiqul Islam, Md. Abdul Ailm, Md. Farzanoor Rahman, Mohammad Nazir Hossain, Md. Morshedul Alam*. “Phytochemical screening and evaluation of antioxidant and cytotoxic activities of Halimeda opuntia.” Journal of Marine Biology and Aquaculture. 2020; June, 6(1): 1-7. (IF: 0.565)

16.  Khadija Rezwana Chowdhury, Abu Nayem, Md. Morshedul Alam, Mohammad Nazir Hossain. “Pharmaceutical potential of endophytes associated with marine sponge and algae from the Bay of Bengal and their contribution to blue economy of Bangladesh.” International Journal of Pharmaceutical Sciences and Research. 2022; May, 13(5): 1000-07. (http://www.ijpsr.com)  (IF: 0.59)

17.  Sultan Abu Saleh Mahmud, Tasnuva Ferdous, Md. Morshedul Alam, Md. Sohag Hossain, Habibul Bari Shozib, Farzana Khalil, Faija Akter, Mohammad Nazir Hossain. “Para-phenylenediamine (PPD) in commercially available Henna preparations in Bangladesh.” Bioresearch Communications. 2022; January, 8(1): 1088-1092.

18.  Tapash Kumar Paul, Md. Morshedul Alam, M. Ziauddin Alamgir, Mohammad Nazir Hossain. “Opportunities and challenges of biosensors for pollution detection and monitoring of the Bay of Bengal.” Bangladesh Maritime Journal. 2021; 6(1).

19.  Toufiqul Islam, Mohammad Nazir Hossain, Md. Morshedul Alam*. “Pharmacological prospects of Cladophoropsis sp. seaweed.” Journal of Earth and Ocean Sciences. 2021; September, 1(1).

20.  Kanchan Chakma, Md. Morshedul Alam #, Dhusarika Chakma, Robiul Hasan Bhuiyan. “Traditional uses of ethno-medicinal plants in Chittagong Hill Tracts (CHTs), Bangladesh: A review.” Journal of Pharmaceutical Research International. 2021; June, 33(30B): 70-79.

21.  Md. Abdul Alim, Md. Farzanoor Rahman, Tamim Ahsan, Toufiqul Islam, Md. Morshedul Alam*, Mohammad Nazir Hossain. “Phytochemical profiling, antioxidant potentiality and antibacterial activity of the ethanolic extracts of Rosenvingea sp. of Bay of Bengal.” Journal of Bangladesh Academy of Sciences. 2021; June, 45(1): 59-71.

22.  Md. Morshedul Alam*. “Dexamethasone as repurposing drug and the possibility of its mitigating role on NRF2-dependent anti-SARS-CoV2 effect.” EC Pharmacology and Toxicology. 2021; January, 9(1):41-44.

23.  Md. Morshedul Alam*. “Therapeutic potential of marine bioactive compounds against SARS-CoV2 infection.” CPQ Medicine. 2020; December, 11(1):1-18.

24.  Mohammad Nazir Hossain, Md. Morshedul Alam. “Oncoprotective role of Ayurvedic herbs and their phytochemicals in cancer therapy”. International Journal of Ayurveda and Pharmaceutical Chemistry. 2020; November, 13(3): 309-332.

25.  Toufiqul Islam, Tamim Ahsan, Md. Abdul Alim, Md. Farzanoor Rahman, Mohammad Nazir Hossain, Md. Morshedul Alam*. “Bioactive compound screening and in vitro appraisal of potential antioxidant and cytotoxicity of Cladophoropsis sp. isolated from the Bay of Bengal.” EC Pharmacology and Toxicology. 2020; September, 8(10): 19-31.

26.  Md. Mostofa Shakil, Md. Abu Jubayer Hossain, Mohammad Abu Sayem Karal, Md. Zohurul Islam, Md. Sadrul Hasan Chowdhury, Md. Anwarul Haque, Md. Morshedul Alam*. “Comparative time-kill assessment of cationic antimicrobial peptide and fluoroquinolone against gram-negative bacteria.” EC Pharmacology and Toxicology. 2020; August, 8(9):117-124.

27.  Md. Morshedul Alam*. “Possibility of NRF2 activation as a priming tool against SARS-COV2 infection.” CPQ Medicine. 2020; August, 10(2):1-5.

28.  Md. Morshedul Alam*. “Essence of antioxidants in aging science: NRF2, a true fact.” CPQ Medicine. 2019; February, 5(5):1-5.

29.  Md. Morshedul Alam*. “Two faces of glucocorticoid receptor (GR) signaling”. EC Pharmacology and Toxicology. 2017; September, ECO, 01:22-24

30.  Shahriar Mahmud, Md. Morshedul Alam*, Aneesa Ansari, Md. Mafizur Rahman, Md. Khorshed Alam and Md. Kamruzzaman Pramanik; “Quality improvement of fresh-cut-fruits by Gamma radiation for Immune-compromised patients.” International Journal of Pharmaceutical Sciences and Research. 2015; August, 6(8):3306-3313. (IF: 0.59)

31.  Tabassum Quibria, Biplab Kumar Das, Tahrim Hasan, Md. Azim Uddin, Md. Morshedul Alam*; “Phytochemical screening and evaluation of analgesic activity of Solanum surattense.” American Journal of Pharmaceutical Sciences and Nanotechnology. 2014; June, 1(1):1-10. (www.uscip.us)

32.  Shabah Shadli, Md. Morshedul Alam*, Anwarul Haque, Begum Rokeya, Liaquat Ali; “Anti-hyperglycemic effect of Zingiber officinale roscoe bark in streptozotocin-induced type 2 diabetic model rats.” International Journal of Pharmacy and Pharmaceutical Sciences. 2014; January, 6(1): 711-716. (www.ijppsjournal.com) (IF: 0.512)

33.  Anzana Parvin, Md. Morshedul Alam, Md. Anwarul Haque, Amrita Bhoumik, Liaquat Ali, Begum Rokeya; “Study of the hypoglycemic effect of Tamarindus indica Linn. seeds on non-diabetic and diabetic model rats.” British Journal of Pharmaceutical Research. 2013; September, 3(4): 1094-1105.

34.  Saifur Rahman, Md. Morshedul Alam*, Muslima Jahan, Md. Rezuanul Islam; “Characterization of Bacillus sp. from Soil Isolates and Comparative Study of Coccinia grandis (L.) Different Leaf Extracts on Antibacterial status Against Bacillus sp.” International Journal of Pharmacy and Pharmaceutical Sciences. 2013; April, 5(2): 235-238. (www.ijppsjournal.com) (IF: 0.512)

35.  Md. Morshedul Alam, Md. Anwarul Haque, Begum Rokeya. “Hypoglycemic effect of Terminalia arjuna on Type 2 diabetic rats”. LAP LAMBERT Academic Publishing (ISBN: 978-3-659-10668-2; 2012-05-16) (https://www.morebooks.de)

36.  Md. Morshedul Alam*, Anwarul Haque, Begum Rokeya and Liaquat Ali; “Anti-hyperglycemic and lipid lowering effect of Terminalia arjuna Bark extract on Streptozotocin induced Type-2 Diabetic Model Rats”. International Journal of Pharmacy and Pharmaceutical Sciences. 2011; October, 3(4): 449-453. (www.ijppsjournal.com) (IF: 0.512)

37.  Md. Morshedul Alam*, M. Azim Uddin, Tahrim Hasan, Tareq Ahmed, Fakhar Uddin, Mudasser Zakaria, Anwarul Haque, Anowar Khasru Parvez; “Evaluation of Analgesic and Anti-inflammatory effect of Terminalia arjuna ethanol extract”. International Journal of Pharmaceutical Sciences and Research. 2011; October, 2(10): 2577-2585. (http://www.ijpsr.com) (IF: 0.59)

38.  T. Hasan, B. K. Das, T. Quibria, Md. Morshedul Alam*, M. A. Uddin; “Phytochemical screening and evaluation of analgesic activity of Xanthium strumarium L.”. Asian Journal of Biochemical and Pharmaceutical Research. 2011; September, 1(3): 455-463. (http://www.ajbpr.com ) 

39.  K. Ushna Sameen Islam, Zafreen Afsana, Md. Morshedul Alam*, M. Azim Uddin, JMA Hannan, Tanzia Akhter Khan, Mirza Golam Sarwar ; Evaluation of Antinociceptive effect of Terminalia arjuna bark ethanol extract. International Journal of Biomolecules and Biomedicine. 2011; August, 1(2):8-16. (http://www.innspub.net) 

40.  B.K. Das, B. Das, F.K. Arpita, Md. Morshedul Alam, A. Uddin, R. Bhattacherjee, and JMA Hannan; “Phytochemical screening and Antioxidant activity of Leucas aspera.”; International Journal of Pharmaceutical Sciences and Research. 2011; July, 2(7):1746-1752. (http://www.ijpsr.com)  (IF: 0.59)

41.  Abdullah Al Bashir, M. Khorshed Alam, M. Mahboob Hossain Khan, Md. Morshedul Alam*, Mirza Golam Sarwar; "Effects of shrimp chitosan on shelf-life extension of orange", International Journal of Biosciences. 2011; June, 1(3): 14-19. (http://www.innspub.net)

42.  Md. Morshedul Alam*, A. A Bashir, M. H. Khan and M. K. Alam; "Antibacterial activity of shrimp chitosan against some local food spoilage bacteria and food borne pathogens" Bangladesh Journal of Microbiology. 2011; 28(1): 37-43. (http://www.bsm.org.bd ) 

43.  Mezba Ul Gaffar, Md. Morshedul Alam*, Azim Uddin, Saurov Roy, JMA Hannan; Study the efficacy of Rhizophora mucornata Poir. leaves for Diabetes therapy in Long Evans rats. International Journal of Biomolecules and Biomedicine. 2011; May, 1(1): 20-26. (http://www.innspub.net) 

44.  Nurunnahar Fayzunnessa, Md. Morshedul Alam*, Azim Uddin, Anzana Parvin, Rahman Saifur; In vivo study on the efficacy of hypoglycemic activity of Spirulina plantesis in Long Evan rats.  International Journal of Biomolecules and Biomedicine. 2011; May, 1(1): 27-33. (http://www.innspub.net) 

45.  Md. Morshedul Alam*, J. Alam, M. Das, A. Haque, L. Ali, B. Rokeya; “Antidiabetic and anti-inflammatory activity of Urtica dioica leaves on STZ induced type 1 diabetic model rats”; International Journal of Pharmaceutical Sciences and Research. 2011; May, 2(5): 1182-1187. (http://www.ijpsr.com)  (IF: 0.59)

46.  Md. Morshedul Alam*, Azim Uddin, Rahman Saifur, Anik Barua, Anwarul Haque; “Evaluation of Antimicrobial and Cytotoxic properties of Leucas aspera and Spilanthes paniculata” International Journal of Biosciences. 2011; April, 1(2): 7-16. (http://www.innspub.net)

47.  Md. Morshedul Alam*, Azim Uddin, Akhlaqur Rahman, Tahrim Hasan, Saurov Roy, Abdullah Al Amin, Rajibul Ahsan, Rezuanul Islam; In vitro Antimicrobial and cytotoxicity screening of Terminalia arjuna ethanol extract” International Journal of Biosciences. 2011; April, 1(2): 31-38. (http://www.innspub.net)

48.  Md. Morshedul Alam*, N. Fayzunnessa, M.A. Haque, A. Uddin, A. Bhowmik, L. Ali, B. Rokeya; “Comparative study of Azadirachta indica leaf powder and its different extracts on glycemic, insulinemic and lipidemic status of type 2 diabetic model rats”, International Journal of Pharmaceutical Sciences and Research. 2011; April, 2(4): 954-960. (http://www.ijpsr.com) (IF: 0.59)

49.  Md. Tipu Sultan, Mahboob Hossain Khan, Md. Lokman Hakim, A.N.K. Mamun, Md. Morshedul Alam*, Md. Rofiqul Islam, Md. Rokibul Islam; “In Vitro plant regeneration from male flowers of Banana”, International Journal of Biosciences. 2011; February, 1(1):1-11. (http://www.innspub.net)

50.  Nazneen Akhter, Md. Morshedul Alam*, Azim Uddin, Feroza Begum, Tipu Sultan, Abul Kalam Azad; “Production of Pectinase by Aspergillus niger Cultured in Solid State Media”; International Journal of Biosciences. 2011; February, 1(1):33-42. (http://www.innspub.net)

51.  Md. Morshedul Alam*, Rubaiyath Rahman, Nirupam Biswas, Sajedur Rahman and Tipu Sultan; “Bactericidal effect of electromagnetic field on water”, Bangladesh Journal of Microbiology. 2010; December, 27(2): 67-70. (http://www.bsm.org.bd)

 

* Corresponding author;       # Co-first author.

 

Abstract/Poster Presentation:

  1. Keito Okazaki, Hayato Anzawa, Hiroshi Kitamura, Yoshiaki Onodera, Md. Morshedul Alam, Daisuke Matsumaru, Takuma Suzuki, Fumiki Katsuoka, Ota Nao, Akira Sakurada, Yoshinori Okada, Masayuki Yamamoto, Takashi Suzuki, Kengo Kinoshita, Hiroki Sekine, Hozumi Motohashi. Enhancer remodeling at the NOTCH3 locus licenses NRF2 for the promotion of a Stem-like phenotype in Non-small Cell Lung Cancers. Environmental Response V/ 17th JBS Biofrontier Symposium (www.nrf2-v.com), Tohoku University Seiryo Auditorium, Sendai, Japan, 2019.09.12-14.
  2. Hiroki Sekine, Keito Okazaki, Md. Morshedul Alam, Hozumi Motohashi. O-GlcNAcylation signaling confers resistance to proteasome inhibitors on cancer cells by increasing NRF1 stability. The 7th Cancer and Metabolism Meeting for the Study in Sendai, Tohoku University Seiryo Auditorium, Japan, 2019.08.01-02.
  3. Md. Morshedul Alam, Hiroki Sekine, Hozumi Motohashi. Selenophosphate synthetase 1 stabilizes NRF2 and regulates its antioxidant response pathway. 85th Japan Biochemical Society Tohoku Branch Annual Meeting, Tohoku University Seiryo Auditorium, Sendai, Japan, 2019.06.08-09.
  4. Keito Okazaki, Hayato Anzawa, Hiroshi Kitamura, Yoshiaki Onodera, Md. Morshedul Alam, Daisuke Matsumaru, Ota Nao, Ryo Sakurada, Katsunori Okada, Fumiki Katsuoka, Masayuki Yamamoto, Takashi Suzuki, Kengo Kinoshita, Hiroki Sekine, Hozumi Motohashi. Enhancer remodeling activates NRF2-NOTCH3 pathway and contributes to stemness in Non-small Cell Lung Cancer. 85th Japan Biochemical Society Tohoku Branch Annual Meeting, Tohoku University Seiryo Auditorium, Sendai, Japan, 2019.06.08-09.
  5. Keito Okazaki, Hayato Anzawa, Hiroshi Kitamura, Yoshiaki Onodera, Md. Morshedul Alam, Daisuke Matsumaru, Fumiki Katsuoka, Ota Nao, Masayuki Yamamoto, Takashi Suzuki, Kengo Kinoshita, Hiroki Sekine, Hozumi Motohashi. De Novo enhancer formation at the NOTCH3 locus licenses NRF2 for the promotion of a steam-like phenotype in Non-small Cell Lung Cancers. 151th IDAC Biannual Meeting Program, Center for Smart Aging Research, IDAC, Tohoku University, 2019.01.25.
  6. Keito Okazaki, Hayato Anzawa, Yoshiaki Onodera, Hiroshi Kitamura, Md. Morshedul Alam, Fumiki Katsuoka, Shu Tadaka, Ikuko Motoike, Masayuki Yamamoto, Takashi Suzuki, Kengo Kinoshita, Hiroki Sekine, Hozumi Motohashi. NRF2-NOTCH3 axis promotes stem-like phenotype of KEAP1-mutant Non-small Cell Lung Cancers. The Joint Symposium of the 13th International Symposium of the Institute Network for Biomedical Sciences and the 28th Hot Spring Harbor International Symposium 2018. Kyushu University, 2018.10.18-19.
  7. Hozumi Motohashi, Tomoaki Ida, Md. Morshedul Alam, Hiroshi Kitamura, Takaaki Akaike. Electrophilic response and sulfur metabolism regulated by KEAP1-NRF2 system. The 91th Annual Meeting of the Japanese Biochemical Society, National Kyoto International Conference Hall, Kyoto, 2018.9.24-26.
  8. Hozumi Motohashi, Tomoaki Ida, Md. Morshedul Alam, Hiroshi Kitamura, Takaaki Akaike. Bright and dark sides of KEAP1-NRF2 system in carcinogenesis. 19th Biennial Meeting of Society for Free Radical Research International (SFRRI 2018), Lisbon, Portugal, 04-07 June 2018.
  9. Hozumi Motohashi, Tomoaki Ida, Md. Morshedul Alam, Hiroshi Kitamura, Takaaki Akaike. Metabolic reprogramming by NRF2 and malignant cancer. 18th Scientific Meeting of the Japanese Society of Anti-Aging Medicine 2018 (JAAM 2018), 2018.05.25-27.
  10. Hozumi Motohashi, Tomoaki Ida, Md. Morshedul Alam, Hiroshi Kitamura, Takaaki Akaike. Biological defense by NRF2 and malignant cancer. The 71st Japan Oxidative Stress Association. Joint academic meeting of the Japan Society of NO. Kyoto Hotel Okura, Kyoto. 2018.05.17-18.
  11. Fujii Shigemoto, Kasamatsu Shingo, Md. Morshedul Alam, Tomoaki Ida, Masanobu Morita, Hideshi Ihara, Akira Nishimura, Tetsuro Matsunaga, Hozumi Motohashi, Takaaki Akaike. Activity control mechanism of nitroso glutathione metabolizing enzyme alcohol dehydrogenase 5 by protein polysulfidation. The 71st Japan Oxidative Stress Association. Joint academic meeting of the Japan Society of NO. Kyoto Hotel Okura, Kyoto. 2018.05.17-18.
  12. Hozumi Motohashi, Tomoaki Ida, Md. Morshedul Alam, Hiroshi Kitamura, Takaaki Akaike. Metabolic features of NRF2-addicted cancer cells. Cold Spring Harbor Meeting Asia “Cancer and Metabolism”, Suzhou, China, 2018.03.26-30.
  13. Takaaki Akaike, Tomoaki Ida, Md. Morshedul Alam, Akira Nishimura, Masanobu Morita, Tetsuro Matsunaga, Hozumi Motohashi. Sulfur respiration in mammals and its implication for tumor biology. Cold Spring Harbor Meeting Asia “Cancer and Metabolism”, Suzhou, China, 2018.03.26-30.
  14. Fujii Shigemoto, Kasamatsu Shingo, Md. Morshedul Alam, Tomoaki Ida, Masanobu Morita, Hideshi Ihara, Akira Nishimura, Tetsuro Matsunaga, Hozumi Motohashi, Takaaki Akaike. Mechanism of detoxification and metabolism of formaldehyde by alcohol dehydrogenase 5 and control by protein polysulfide formation. The 17th Molecular Prevention and Environmental Medicine Study Group, Mie University School of Medical Hospital, Japan. 2018.02.02-03.
  15. Tetsuro Matsunaga, Akira Nishimura, Shingo Kasamatsu, Md. Morshedul Alam, Tomoaki Ida, Masanobu Morita, Ihara Hideshi, Fujii Shigemoto, Sho Shimoda,  Masahiro Nishida, Hozumi Motohashi, Akaike Takaaki. Development of nitrosoglutathione reductase (GSNOR) selective deficient mouse. The 90th Japan Biochemical Society Convention, Kobe. 2017.12.6-9.
  16. Hiroki Sekine, Keito Okazaki, Md. Morshedul Alam, Hozumi Motohashi. O-GlcNAcylation signal confers resistance to proteasome inhibitors on cancer cells by increasing NRF1 stability. 12th International Symposium of the Institute Network, Institute of Medical Science, The University of Tokyo (IMSUT), Tokyo, Japan, 2017.11.28-29.
  17. Jung Minkyung, Akira Nishimura, Shingo Kasamatsu, Md. Morshedul Alam, Tomoaki Ida, Tetsuro Matsunaga, Fujii Shigemoto, Hideshi Ihara, Hozumi Motohashi, Takaaki Akaike. Polysufidation regulates enzymatic activity of Alcohol dehydrogenase 5 (Adh5) protein. 70th Annual Meeting of the Japanese Society of Oxidative Stress, Tsukuba International Congress Center, Tsukuba, Japan, 2017.06.28-29. (https://www.sfrrj2017.org/pdf/sfrrj2017_Abstracts.pdf)
  18. Hozumi Motohashi, Akira Nishimura, Masanobu Morita, Md. Morshedul Alam, Tomoaki Ida, Akaike Takaaki. Control enzyme activity of alcohol dehydrogenase 5 by polysulfidation. Physiological Research Organelle Institute, Natural Sciences Research organization, Okazaki Integrated Bioscience Center, Okazaki.　2017.5.31-6.1.
  19. Tomoaki Ida, Shingo Kasamatsu, Md. Morshedul Alam, Masanobu Morita, Ihara Hideshi, Akira Nishimura, Tetsuro Mastsunaga, Fujii Shigemoto, Hozumi Motohashi, Akaike Takaaki. Function of protein polysulfide formation in enzyme activity control of alcohol dehydrogenase 5. The 17th Japan Society for Academic Conference, Awa Tourist Hotel, Tokushima.　2017.5.19-20.
  20. Chazia Glulamo Abdula, Shingo Kasamatsu, Akira Nishimura, Md. Morshedul Alam, Tomoaki Ida, Tetsuro Matsunaga, Fujii Shigemoto, Ihara Hideshi, Hozumi Motohashi, Akaike Takaaki. Alcohol dehydrogenase 5 protein/enzyme activity control function of polysulfidation. The 90th Japan Association of Bacteriological Society, Sendai International Conference Hall　2017.3.19-21. 
  21. Md. Morshedul Alam, Linh Thi Thao Nguyen, Keito Okazaki, Nao Ota, Hiroshi Kitamura,Hiroki Shima, Kazuhiko Igarashi, Hiroki Sekine, Hozumi Motohashi. Glucocorticoid receptor signaling represses antioxidant response by inhibiting NRF2-dependent histone acetylation. 10th Retreat Conference, Tohoku University, Sendai, Japan. 2017.1.14.
  22. Nguyen Thi Thao Linh, Keito Okazaki, Hiroki Sekine, Md. Morshedul Alam, Hozumi Motohashi. Contribution of Trim24 to regulation of antioxidant gene expression mediated by NRF2. 10th Retreat Conference, Tohoku University, Sendai, Japan. 2017.1.14.
  23. Md. Morshedul Alam, Linh Thi Thao Nguyen, Hiroki Shima, Kazuhiko Iharashi, Hiroki Sekine, Hozumi Motohashi. Dexamethasone-induced Glucocorticoid Receptor Represses Antioxidant Gene Expression Mediated by NRF2. 89th Annual Meeting of Japan Biochemical Society, Sendai, Japan. 2016.09.25-27; IP-190.
  24. Hiroki Sekine, Koichiro Kato, Aina Fukuda, Norio Suzuki, Keito Okazaki, Md. Morshedul Alam, Tadayuki Tsujita, Akira Kobayashi, Masayuki Yamamoto, Hozumi Motohashi. Molecular mechanism of NRF1 degradation. 89th Annual Meeting of Japan Biochemical Society, Sendai, Japan. 2016.09.25-27.
  25. Shingo Kasamatsu, Md. Morshedul Alam, Tomoaki Ida, Tetsuro Matsunaga, Shigemoto Fujii, Hideshi Ihara, Hozumi Motohashi, Takaaki Akaike. Function of protein polysufidation on regulation of alcohol dehydrogenase 5 activity. 89th Annual Meeting of Japan Biochemical Society, Sendai, Japan. 2016.09.25-27.
  26. Kasamatsu S, Md. Morshedul Alam, Ida T, Matsunaga T, Fujii S, Ihara H, Motohashi H, Akaike T.  Novel enzyme activity control mechanism of alcohol dehydrogenase 5 by protein polysulfuration.  The 69th Annual Meeting of the Japanese Society of Oxidative Stress. Sendai, Japan. 2016.8.30-31.
  27. Kasamatsu S, Md. Morshedul Alam, Ida T, Matsunaga T, Fujii S, Ihara H, Motohashi H, Akaike T.  Regulatory mechanisms of alcohol dehydrogenase 5 activity via protein polysulfuration.  The 9th International Conference of the Biology, Chemistry and Theapeutic applications of nitric oxide.  Sendai International Center (Sendai) 2016.5.20-22.
  28. Md. Morshedul Alam, Hiroshi Kitamura, Hozumi Motohashi. Establishment of straightforward and conditional knockout mice of Fancd2 gene. 9th Retreat conference, Tohoku University, Sendai, Japan. 2016.01.23; p-65.
  29. Kasamatsu Shingo, Md. Morshedul Alam, Ida Tomoaki, Tetsuro Matsunaga, Fujii Shigemoto, KyoHara Xiu, Akaike Takaaki, Motohashi Hozumi. Enzyme activity control mechanism of alcohol dehydrogenase 5 via protein Polysulfur. 38th Japan molecular biology Society annual / 88th Japanese biochemical Society Congress joint Meeting. Kobe Port Island. Kobe. 2015.12.1-4.
  30. Fujii Shigemoto, Md. Morshedul Alam, Tomoaki Ida, Tetsuro Matsunaga, Kasamatsu Shingo, KyoHara Xiu, Akaike Takaaki, Motohashi Hozumi. Active control mechanism of alcohol dehydrogenase 5 by the protein S- polythiol. 15th Annual Meeting of the Japanese Society of NO. Senri Life Science Center Osaka (2015.6.26-27).
  31. Goto Maki, Hiroshi Kitamura, Md. Morshedul Alam, Takeshi Haseba, Teruko Yamamoto, Masayuki Yamamoto, Kasamatsu Shingo, Ida Tomoaki, Akaike Takaaki, Motohashi Hozumi. Oxidative stress defense and metabolic control by Glutathione-dependent formaldehyde dehydrogenase ADH3. Research PlaNet2015. Umeda Sky Building Tower West Osaka. (2015.6.20-21).
  32. Fujii Shigemoto, Md. Morshedul Alam, Tomoaki Ida, Tetsuro Matsunaga, Kasamatsu Shingo, KyoHara Xiu, Akaike Takaaki, Motohashi Hozumi. The role of protein S- polythiol for the active expression of alcohol dehydrogenase 5. 68th Annual Meeting of the Japanese Society of oxidative stress. Kagoshima Public Access Center Kagoshima (2015.6.11-12).
  33. Md. Morshedul Alam, Shingo Kasamatsu, Maki Goto, Hiroshi Kitamura, Tomoaki Ida, Takaaki Alaike, Hozumi Motohashi; Human ADH5 polymorphisms affect susceptibility to electrophilic stresses. 81th Japan Biochemical Society Tohoku Branch Symposium, Tohoku University, Sendai, Japan (9th May, 2015, p-60).
  34. Ida Tomoaki, Md. Morshedul Alam, Matsunaga Tetsuro, Fujii Shigemoto, KyoHara Xiu, Motohashi Hozumi, Akaike Takaaki; Formaldehyde detoxification metabolism mechanism by active sulfur molecules and ADH3. 14th Molecular Preventive Environmental Medicine Society symposium, Osaka City University School of Medicine, Osaka, Japan (February, 2015, p-46)
  35. Md. Morshedul Alam, Hozumi Motohashi; Establishment of conditional Fancd2 knockout mice to clarify the maintenance program of intra-nuclear redox homeostasis. 7th Retreat Conference, Tohoku University, Sendai, Japan (January, 2014, p-54).
  36. Md. Morshedul Alam, Sang Ah Lee, Gwanpyo Koh and Dae Ho Lee; Changes of Hepatic Cellular Retinol-Binding Protein-I (CRBP-I) in Relation to Fatty Liver Diseases. Journal of Diabetes Investigation, 2012; November, 3 (suppl-1):159.
  37. A. Parvin, MM. Alam, A. Haque, A. Bhowmik, M. Akhter, L. Ali, B. Rokeya; “Studies on the antidiabetic effects of Tamarindus indica (Tamarind) Linn. seeds on Nondiabetic, Type 1 and Type 2 diabetic model rats”, Diabetes and Endocrine Journal, 2010, 39(1): 24-25.
  38. Morshed Alam, Haque Anwarul, Fayzunnessa Nurunnahar, Ali Liaquat, Rokeya Begum; “Anti-hyperglycemic and Anti-lipidemic Effect of Terminalia arjuna ethanol extract on Streptozotocin induced Type-2 Diabetic Model Rats”; International Young Scientists Congress-2009: Young Scientists for Development, Dhaka, Bangladesh, December-2009, p-45

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